Environmental Radiation Effects on Mammals: A Dynamical Modeling Approach

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Publisher	Springer; 2010th edition
ISBN 13	9781489982384
ISBN 10	1489982388
Author	Olga A. Smirnova
Book Format	Paperback

Language	English
Book Description	Themonographisdevotedtothetheoreticalstudiesofradiationeffectsonmammals. It summarizes the results obtained by the author over the past 30 years, most of them being of high priority. In the course of these studies, a single approach to the modeling of radiation effects on mammals has been elaborated. Speci?cally, in the framework of the developed deterministic mathematical models, the effects of both acute and chronic irradiation in a wide range of doses and dose rates on vital body systems (hematopoiesis, small intestine, and humoral immunity), as well as on the development of autoimmune diseases, are investigated. The radiation effects on the mortality dynamics in homogeneous and nonhomogeneous(in radiosensitivity) mammalian populations are also studied by making use of the developed stochastic models. The most appealing feature of these mortality models consists of the fact that they account for the intrinsic properties of the exposed organism. Namely, within these models the stochastic biometrical functions are calculated proceeding from statistical characteristics and dynamics of the respective critical body system (hematopoiesis or small intestine). The performed theoretical investigations contribute to the development of the system and quantitative approaches in radiation biology and ecology. These studies elucidate the major regulatory mechanisms of the damage and recovery processes running in the vital body systems of exposed mammals and reveal the key par- eters characterizing the processes.
About the Author	Dr. Olga Andreevna Smirnova is currently a physicist and researcher at the Federal State Unitary Enterprise Research and Technical Center of Radiation-Chemical Safety and Hygiene, Moscow, Russia. She received her Doctor of Physical and Mathematical Sciences degree from Moscow State University, Russia. Dr. Smirnova's fields of study and expertise are modeling the dynamics of various biological systems in mammals exposed to acute/chronic radiation. Dr. Smirnova is associate member of the Scientific Commision F (Life Sciences as Related to Space) of Committee on Space Research (COSPAR). She has authored over 140 articles published in scientific journals and scientific monographs in the fields of mathematical modeling, biophysics, and space science.
Publication Date	19 October 2014
Number of Pages	230 pages

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